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NFL Week 6 Prop Picks And Best Prop Bet Predictions

Catch all the Top NFL Prop Picks & Best Prop Bets right here, every week, on Big Guy Fantasy Sports!

Every week, Colby Conway and Bob Lung use the Forecaster Consistency Tool to help you win your Fantasy Football Prop Bets! Follow them @colbyconway and @bob_lung. If you are looking for some weekly NFL player props, you’ve come to the right place! There are ample player props out there, but Bob Lung and Colby Conway provide their favorite player props to target for this week’s action across the National Football League.

The consistency concept can be applied to player props, just like it has for daily fantasy sports and seasonal fantasy football, so find those consistent players to give yourself the best chance of winning some money betting on player props. Make sure to check out the Prop It Like It’s Hot podcast for even more player props for this week!

NFL Week 6 Prop Picks – 10/11/25 – Prop It Like It’s Hot!

NFL Week 6 Prop Picks And Best Prop Bet Predictions


Week 6 NFL Prop Picks

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Matthew Golden OVER 44.5 Receiving Yards

Per FantasyPoints, the Bengals have allowed the second-most yards per game to the slot and the league’s highest yards per route run metric. Golden has been the lead slot WR for the Packers since Jayden Reed got hurt earlier in the season, and slot receivers have been great against Cincy. Dax Hill is a liability in coverage, and Golden is the only Packer with a 14+ percent target share in each of the team’s last two games. Trust the matchup and the talent.

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Mason Taylor OVER 34.5 Receiving Yards

Taylor has seen a 20+ percent target share in each of the last two weeks, and his target share has increased every single week. With Garrett Wilson dealing with Patrick Surtain all morning, expect Justin Fields to look elsewhere, and lately, his second option has been rookie tight end Mason Taylor. The matchup is far from ideal, and Denver has been tough on opposing tight ends, but Fields needs to throw the ball somewhere, and Taylor has been reliable the last two weeks (14 receptions on 19 targets for 132 yards).


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Jacory Croskey-Merritt – Longest Rush OVER 15.5 Yards

Croskey-Merritt has the second-highest explosive run rate amongst running backs with at least 40 carries on the season, and this matchup against Chicago on Monday is TASTY! The Bears have allowed the fifth-highest YPC on man/gap runs, and according to FantasyPoints, JCM is a top-five RB in terms of success rate on man/gap runs. He played a season-high snap share last week, and if this trend continues, he’ll have more than enough opportunities to rip off a big play.

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Alec Pierce OVER 2.5 Receptions (+124) and OVER 29.5 Receiving Yards (-113)

Pierce has missed the past two weeks with a concussion. He’s back this week and ready to go! In his two weeks before his concussion, he had four catches for 68 yards and four catches for 67 yards. So, why is his prop line sitting at 2.5 catches and 29.5 yards? Don’t know. Don’t care! Lock in those two props before the line changes.

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Sterling Shepard – OVER 3.5 Receptions (-113)

When Chris Godwin is out, Shepard produced three weeks of over four receptions in each game. Chris Godwin is out for this week. This should be another shootout as they take on the 49ers. The 49ers have given up an average of 12 catches per game. Therefore, Shepard should get his four catches again this week.

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Emanuel Wilson – OVER 19.5 Rushing Yards (-115)

Wilson is the backup to Josh Jacobs. However, in many of these high-scoring/bad run defenses, Wilson is getting quite a number of touches per game. In the last two games, he’s rushed for 25 and 44 yards. Therefore, going against the Bengals’ porous defense, going over 19.5 yards seems too easy.


You can find & follow @colbyconway and @bob_lung on the X! And thank you for joining us for our Week 6 NFL Prop Picks and Best Bets!

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