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NFL Week 12 Prop Picks And Best Prop Bet Predictions Copy

Catch all the Top NFL Prop Picks & Best Prop Bets right here, every week, on Big Guy Fantasy Sports!

Every week, Colby Conway and Bob Lung use the Forecaster Consistency Tool to help you win your Fantasy Football Prop Bets! Follow them @colbyconway and @bob_lung. If you are looking for some weekly NFL player props, you’ve come to the right place! There are ample player props out there, but Bob Lung and Colby Conway provide their favorite player props to target for this week’s action across the National Football League.

The consistency concept can be applied to player props, just like it has for daily fantasy sports and seasonal fantasy football, so find those consistent players to give yourself the best chance of winning some money betting on player props.

NFL Week 10 Prop Picks – 11/22/25 – Prop It Like It’s Hot!

NFL Week 12 Prop Picks And Best Prop Bet Predictions


Week 12 NFL Prop Picks

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Kenneth Walker OVER 61.5 Rushing Yards

The Titans have two good run defenders on the interior of its defensive line, but Seattle can
maximize Walker’s output by not running him in the A-gap against this defense. Take a look at
the below data (also mentioned in the Consistently Cashin’ article) on Walker’s numbers this
season depending on the rush location, courtesy of Fantasy Points Data.

The Titans have allowed over five yards per carry on runs to the C and D gap this season, per
FantasyPoints data, and if the comments are true that they want to give Walker more work, he’ll
breeze past this line in a game where Seattle is two touchdown favorites.

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Tetairoa McMillan OVER 4.5 Receptions

The team should continue to utilize McMillan in the slot because it helps quarterback Bryce
Young, and simply put, McMillan has crushed in the slot this season. Per FantasyPoints Data,
he’s posted 2.57 yards per route run and a 152.3 passer rating when targeted. Furthermore,
the 49ers have allowed the fifth-most yards per route run and the most fantasy points per game
to slot receivers this season, per FantasyPoints. It simply makes too much sense, so it should
happen. Over the last four weeks, the rookie wideout has averaged six receptions, nine targets,
and 83.8 yards per game.


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Caleb Williams OVER 1.5 Passing Touchdowns

The Steelers have allowed five of 10 opposing quarterbacks to throw for 2+ touchdowns in a
game this season, and I think Williams will make it six of 11. Sure, he only has one passing
touchdown over the last two weeks, and two or more passing scores in just three games this
season, but the Steelers have been decimated by opponents through the air the last couple of
weeks. Let’s chase some plus odds with this one.

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Andrei Iosivas OVER 3.5 Receptions / 35.5 Receiving Yards

After the spitting debacle last weekend with Jamar Chase and this week’s suspension, Iosivas has the #2 spot in the Bengals’ passing game. White, I believe there was a second spitter, this does open the door of opportunity this week. Back in Week 9, Iosivas had five catches for 66 yards. The bar is set very low for both receptions and yards; I can’t help myself from picking both. New England has a solid defense, but not an overwhelming one. I’ll take the over for both.

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Kayshon Boutte OVER 2.5 Receptions / 30.5 Receiving Yards

Yep, I’m picking the WR2 on the other team in this Bengals versus Patriots clash this weekend. Boutte has missed a few weeks due to injury. He’s healthy and he’s back to pair up with Drake Maye. In those four weeks prior to his injury, Boutte went over 30.5 receiving yards in 100% of the games and 75% over the 2.5 receptions. This is the Bengals defense that we are talking about. So, this seems like a no-brainer for both of them this week.

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Tyjae Spears OVER 17.5 Receiving Yards

 With so many injuries in the Titans pass offense, one would believe that Spears will see many passes this weekend versus the Seahawks. However, Vegas does not and that’s okay. Seattle has given up the second most receptions (avg per game) and the fifth most receiving yards (avg per game). Seattle could easily jump out to a big lead and force lots of garbage time for the Titans. That’s where Spears gets the most involved.


You can find & follow @colbyconway and @bob_lung on the X! And thank you for joining us for our Week 10 NFL Prop Picks and Best Bets!

Colby Conway has been writing in the fantasy sports industry since 2014, focusing on fantasy football, fantasy baseball, daily fantasy sports, and sports betting (primarily player props). He is a die-hard Houston Texans fan, and is a participant in the King's Classic fantasy football leagues.

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